Monoclonal Antibody Production Service

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We specialize in high quality monoclonal antibodies, particularly those which are difficult to produce. Our two main foci are robust screening methodologies and excellent antigen design.

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Fusion Antibodies typically specialise in designing non-standard projects for difficult to produce antibodies and achieve this by carefully designing our screening strategies. For example; we have designed strategies for generating antibodies to differentiate between phosphorylated and non-phosphorylated forms of a protein and strategies to generate non-interacting pairs of antibodies against the same protein.

We can also run simple projects for more straight forward targets.

Using techniques in constant development since 2001, our lab achieves high fusion success rates which increases the likelihood of a successful outcome of your project. We have completed over 200 antibody generation projects for a wide range of clients, from small biotech to large pharmaceutical companies. We offer a range of options for developing monoclonal antibodies. Our goal is to allow access to the production of high quality antibodies to a wide variety of researchers with flexible pricing. We provide a “core” service including immunization of mice, hybridoma fusion, screening and cloning but now also have options to include additional services such as adaptation to supplement free media.

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Contact us about Monoclonal Antibody Production Services

 

Our monoclonal antibody development service produces high quality hybridoma cell lines.

We use 3D modelling software to assist us in designing high quality peptide antigens to represent your protein of interest. This allows us to develop high quality peptides which we know are accessible on the protein surface and immunogenic. We also model and overlay these peptide sequences to make sure they are conformationally similar to the target protein. The result is an immunogen which accurately represents the intended target and therefore better antibodies with higher affinities. Our custom antibody production service is based on the classic Kohler and Milstein technique for the production of monoclonal antibodies becuase we believe it the best technique for high quality monoclonals.

Monoclonal Antibodies 3D structure peptide mapping

Our approach is to listen to your final requirements and work with you to design a mile-stoned work package to deliver on your exact requirements for your monoclonal antibody development program. The murine antibodies we manufacture are perfect as high quality research antibodies and when your project is ready we can humanize them for use in the clinic.

Fusion Antibodies are experts at monoclonal antibody generation and pride ourselves on the following key points:

  • Many years experience in the Antibody Development field
  • Hundreds of successful projects
  • Extensive knowledge of antigen design, expression and purification
  • We can offer complete packages to move your antibody forward
  • Client-focused
  • We will work with your team closely to achieve your goals
  • UK-based company
  • Mile-stoned payments

We have designed techniques for generating antibodies to differentiate between phosphorylated and non-phosphorylated forms of a protein, strategies to generate non-interacting pairs of antibodies against the same protein and methods for targeting highly specific epitopes on the target. We can also run simple projects for more straight forward targets.

For more information contact us on the form below, email info@fusionantibodies.com or call UK +44 (0)28 9043 2800

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